Major Negative effects could possibly be extra probably in older Grown ups and people who are overweight, malnourished, or debilitated.

There isn't any information on the effects of codeine on milk production. Due to the prospective for critical adverse reactions, together with excess sedation, respiratory depression, and Loss of life within a breastfed toddler, suggest sufferers that breastfeeding is just not suggested in the course of remedy with acetaminophen and codeine phosphate tablets (see WARNINGS).

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Habit, Abuse, and Misuse Because the utilization of acetaminophen and codeine phosphate tablets expose people and other consumers to your risks of opioid addiction, abuse, and misuse, which can result in overdose and Dying, evaluate each patient’s risk previous to prescribing and reassess all individuals regularly for the event of these behaviors and problems (see WARNINGS).

Generally talk to your healthcare company to make sure the data exhibited on this site applies to your individual conditions.

All through pregnancy, this medication really should be made use of only when Plainly desired. It may well harm an unborn little one. Go over the hazards and Added benefits along with your medical doctor.

Tell sufferers that opioids could lead to a exceptional but likely lifestyle-threatening problem resulting from concomitant administration of serotonergic medications. Alert clients in the signs or symptoms and indications of serotonin syndrome check here and to hunt healthcare interest straight away if signs develop.

Reveal to sufferers and caregivers that naloxone’s effects are website momentary, and that they must connect with 911 or more info get unexpected emergency professional medical assist without delay in website all instances of recognised or suspected opioid overdose, even though naloxone is administered (see OVERDOSAGE).

Lengthy-expression studies To guage the carcinogenic prospective of The mix of codeine and acetaminophen haven't been performed.

Frequently Assess people using a history of seizure Ailments for worsened seizure control through acetaminophen and codeine phosphate tablets therapy.

Teach clients and caregivers on how to recognize respiratory depression and emphasize the value of contacting 911 or having crisis healthcare aid right away within the occasion of a acknowledged or suspected overdose (see WARNINGS, Lifetime-Threatening Respiratory Despair).

Narcotic analgesics need to be avoided during labor if supply of the premature infant is expected. In case the mother has received narcotic analgesics all through labor, new child infants ought to be noticed intently for signs of respiratory depression.

Don't abruptly discontinue acetaminophen and codeine phosphate tablets in individuals who could be physically depending on opioids. Immediate discontinuation of opioid analgesics in people who will be bodily dependent on opioids has resulted in serious withdrawal signs, uncontrolled ache, and suicide.

To examine the Affected person Information and facts (or other academic material) that should feature their naloxone. here Emphasize the importance of executing this just before an opioid emergency transpires, Therefore the patient and caregiver will know how to proceed.